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Postdoctoral Researcher in Molecular Cancer Therapy

Karolinska Institutet (KI)
Stockholms län
för 1 dag sedan

Do you want to contribute to top quality medical research?

Postdoctoral Researcher in molecular mechanisms of anti-leukemic therapy

Come join the Rudd Lab! We are seeking a postdoctoral researcher to join our group and embark on a collaborative and translational research project together with the Herold lab, with the ultimate goal of providing cancer patients with improved treatment options. We are a young and dynamic team affiliated with the Department of Oncology-Pathology and physically located at SciLifeLab in Stockholm.

Your mission

Our research is centred upon antimetabolite cancer therapies, which remain standard-of-care for many cancers including leukaemias. However, their efficacy can vary, and the underlying molecular mechanisms can remain unclear. Thus, we aim to further our basic understanding of how these agents exert their therapeutic effects, to understand why in some instances they work and in others they do not, and leverage this information to design therapy improvements. In this project, we will focus upon the treatment of T-cell acute lymphoblastic leukaemia.

The successful candidate will employ an array of biochemical, molecular and cell biology-focused approaches, together with collaborating with our clinical partners in the Herold lab, (Department of Women’s and Children’s Health), to fulfil the translational research goals of this project.

This call is part of the KI-SciLifeLab Clinical Translational Postdoc Program with the purpose of promoting interaction between the SciLifeLab research environment and clinical research environments at Karolinska Institutet. The postdocs that are recruited to the program will form a network with the support of the SciLifeLab Committee KI.

Your profile

To be eligible for employment as a postdoctor, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.

Other requirements of the position include:

  • Keen interest in translational cancer research
  • Well-versed with standard biochemical, molecular and cell biology techniques
  • First author publication/preprint
  • Effective communication skills – written and oral. Fluency in English.
  • Ability to work in a team
  • Experience in bioinformatics

Desired skills:

  • Research experience in genome stability, nucleotide metabolism, molecular pharmacology, or leukaemia biology/therapy
  • Experience with preclinical cancer models and patient-derived material

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Solna

Sean Rudd´s Group
Nikolas Herold´s Group
Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

  • PhD certificate
  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 30th September.

The application is to be submitted through the Varbi recruitment system.

The position is 2 years with possibility of extension.

Want to make a difference? Join us and contribute to better health for all!

Anställningsform: tidsbegränsad anställning | Anställningens omfattning: heltid | Antal lediga befattningar: 1 | Sysselsättningsgrad: 100 | Ort: Solna | Län: Stockholms län | Land: Sweden | Referensnummer: STÖD 2-3360/2025 | Kontakt: Sean Rudd [email protected], Nikolas Herold [email protected], | Facklig företrädare: Helen Eriksson, OFR [email protected], Henry Wölling, Seko [email protected], Per Hydbring och Nick Tobin, SACO [email protected]/[email protected], | Publicerat: 2025-08-27 | Sista ansökningsdag: 2025-09-30
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